PRIMTECH3R

PRIMTECH3R

Topic: HORIZON-INFRA-2024-TECH-01-01

Duration: 36 months

Start date: 1 April 2025

Grant agreement: 101188158

Web: https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/projects-details/43108390/101188158/HORIZON?isExactMatch=true&programmePeriod=2021%20-%202027&frameworkProgramme=43108390&programmePart=43108514&order=DESC&pageNumber=NaN&sortBy=title&tenders=false&closed=false&destination=44798979

Total request Grant by Consortium: € 8,999,960,00

Total request Grant by BBMRI-ERIC: € 578,125.00

Project description: The use of mouse models in biomedical research has been pivotal in understanding human diseases due to their genetic and physiological similarities to humans. However, concerns on ethics and translatability have prompted a shift towards alternative methods such as complex in vitro models (CIVMs). PRIM-TECH3R addresses this shift by leveraging advanced technologies to develop reliable mouse and human CIVMs for preclinical studies, aiming to reduce and refine the use of animal models. Through standardised protocols and robust validation procedures, the project will create state-of-the-art in vitro models from mouse disease models, complementing existing in vivo models. This initiative aligns with EU policy objectives and societal demands to address phasing out of animal testing in biomedical research. The project will establish a comprehensive repository of preclinical resources, ensure open access, and foster collaboration between research infrastructures and the biomedical industry. Training programmes will equip personnel with the necessary skills to provide CIVMs to the research community. By achieving these objectives, PRIM-TECH3R aims to advance the state-of-the-art in research infrastructures, facilitate industrial exploitation, and contribute to transformative changes in biomedical research practices.